POSITION SUMMARY:
The individual is responsible for leading the strategic optimization, financial performance, and operational execution of the health system’s 340B program. This role serves as a system-level leader accountable for maximizing the value of the 340B program to expand patient access, improve affordability, and drive sustainable financial performance.
This leader will partner across pharmacy, finance, compliance, and clinical operations to ensure accurate program execution, compliant growth, and continuous performance improvement across contract pharmacy, mixed-use settings, and eligible sites.
The leader will also play a key role in translating 340B opportunity into actionable initiatives, ensuring alignment between program strategy, operational workflows, and financial outcomes.
Position: Senior Manager, 340B Optimization
Department: System Hospital Pharmacy
Schedule: Full Time
ESSENTIAL RESPONSIBILITIES / DUTIES:
1. 340B Strategy & Optimization
Lead development and execution of a system-wide 340B optimization strategy aligned with organizational financial and access goals
Identify and implement opportunities to expand program capture, improve margin performance, and optimize contract pharmacy networks
Partner with executive leadership to translate 340B value into sustainable patient access strategies
2. Financial Performance & Analytics
Own performance tracking of the 340B program, including:Savings realization and margin optimization
Contract pharmacy performance
Capture rate and leakage analysis
Develop and maintain dashboards and reporting to support data-driven decision making
Partner with finance to ensure alignment between 340B performance and system financial targets
3. Operations & Program Execution
Oversee operational processes supporting 340B, including:Split-billing optimization
Eligibility workflows
Inventory and replenishment alignment
Identify and resolve operational gaps that impact program capture or compliance
Partner with pharmacy operations teams to ensure consistent execution across sites
4. Contract Pharmacy Optimization
Evaluate and optimize contract pharmacy network performance
Identify opportunities to:Improve financial yield
Enhance patient access
Reduce operational inefficiencies
Support development of contracting strategies and performance expectations
5. Compliance & Risk Management
Partner closely with compliance leaders to ensure adherence to:HRSA requirements
State and federal regulations
Support audit readiness and remediation efforts
Ensure optimization strategies are designed with a compliance-first mindset
6. Cross-Functional Leadership
Collaborate with:Pharmacy operations (inpatient, outpatient, specialty)
Finance and revenue cycle
Compliance and legal
IT / split-billing vendors
Serve as a key liaison to align stakeholders on 340B priorities and execution plans
7. Innovation & Program Growth
Identify and implement innovative solutions to improve 340B performance (e.g., workflow redesign, technology enablement, analytics tools)
Support evaluation of new program opportunities, including:New site eligibility
Service line expansion
Enhanced patient engagement models
Leadership Responsibilities
Provide direct oversight of analysts, managers, or program leads supporting 340B operations
Establish clear performance goals and accountability structures
Foster a culture of ownership, transparency, and continuous improvement
Support development of future leaders within the pharmacy organization
(The above statements in this job description are intended to depict the general nature and level of work assigned to the employee(s) in this job. The above is not intended to represent an exhaustive list of accountable duties and responsibilities required)
JOB REQUIREMENTS
REQUIRED EDUCATION AND EXPERIENCE:
Bachelor’s degree in Pharmacy, Business, or related field
3-5+ years of progressive experience in pharmacy, with strong exposure to:340B program management or optimization
Pharmacy operations (health system preferred)
Financial and performance analytics
Experience within an academic medical center or large integrated delivery network.
Experience supporting specialty pharmacy, infusion services, or complex distribution models.
Experience presenting supply chain strategies and financial analyses to executive leadership and governance committees.
Or equivalent combination of education and experience.
PREFERRED EDUCATION AND EXPERIENCE (If none, please enter “N/A”):
PharmD or MBA preferred
Experience working in a complex health system or academic medical center strongly preferred
CERTIFICATIONS, LICENSES, REGISTRATIONS REQUIRED (If none, please enter “N/A”):
N/A
CERTIFICATIONS, LICENSES, REGISTRATIONS PREFERRED (If none, please enter “N/A”):
MA Pharmacist License
KNOWLEDGE, SKILLS & ABILITIES (KSAs) (If none, please enter “N/A”):
Knowledge of DSCSA compliance, pharmaceutical supply chain regulations, and drug shortage management frameworks – all related to 340B
Advanced analytical, financial modeling, and executive communication capabilities.
Compensation Range:
$122,000.00- $177,000.00This range offers an estimate based on the minimum job qualifications. However, our approach to determining base pay is comprehensive, and a broad range of factors is considered when making an offer. This includes education, experience, skills, and certifications/licensures as they directly relate to position requirements; as well as business/organizational needs, internal equity, and market-competitiveness. In addition, BMCHS offers generous total compensation that includes, but is not limited to, benefits (medical, dental, vision, pharmacy), discretionary annual bonuses and merit increases, Flexible Spending Accounts, 403(b) savings matches, paid time off, career advancement opportunities, and resources to support employee and family well-being.
NOTE: This range is based on Boston-area data, and is subject to modification based on geographic location.
Equal Opportunity Employer/Disabled/Veterans
According to the FTC, there has been a rise in employment offer scams. Our current job openings are listed on our website and applications are received only through our website. We do not ask or require downloads of any applications, or “apps” job offers are not extended over text messages or social media platforms. We do not ask individuals to purchase equipment for or prior to employment.